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Molecular Biology / Cell Biology > Signal Transduction
Product
 
Information
Code:63-151

Backgroud: Mrc1 (Mediator of replication checkpoint 1) is a S-phase checkpoint
protein of Schizosaccharomyces pombe found at replication forks required for
phosphorylation and activation of Cds1 during DNA replication stress where it forms
a replication-pausing complex and is phosphorylated by Rad3 and Tel1 kinases. The
phosphorylated form of Mrc1 is detected by a change in the electrophoretic mobility.
Human homolog of Mrc1 is claspin.
Applications
1) Western blotting (x3000 dilution)
2) Other applications were not tested.
Specification
Immunogen: Purified recombinant protein containing amino acids 1~317 of Mrc1
Form; Undiluted rabbit antiserum added with 0.05 % sodium azide

Reference: This product is described and used in reference 1
1. Zhao H. Mol Cell Biol 23: 8395 (2003)
 
 
Code
Quantity
                  Price
 
63-151
50 ul
300 USD

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