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70-101

Storage: Ship at 4℃ and store at -20℃.

Validation of Reactivity: Specificity has been validated with siRNA of human DSN1 for WB and IF. Reacts with mouse rat

Immunogen: Recombinant GST-DSN1 (1-356 aa)

Applications:
1) Western blotting (1000 fold dilution)
2) Immunofluorescence-staining (1000 fold dilution)

Product: Rabbit antiserum added with 0.05% sodium azide. Anti-GST antibodies have been removed from the serum with affinity column conjugated with GST

Background: DSN1 / Mis13 (human: 356 aa. 40 kDa) is part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. Defects in kinetochore proteins often lead to aneuploidy and cancer. It is a component of the MIS12 complex composed of MIS12 DSN1 NSL1 and PMF1 and also interacts with CASC5 CBX3 and CBX5. Note that DSN1 protein is expressed in actively dividing cells.
 
 
Code
Quantity
                  Price
 
70-101
100 ul
350 USD

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