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73-100

Storage: Ship at 4℃ and store at -20℃

Immunogen: Mouse E16 embryonic cerebral cortex extracts

Applications
1. Immunocytochemistry
2. Immunohistochemistry
This antibody doesn’t work in immunoblotting. O

Isotype: Rat IgG2b κ

Form: Purified monoclonal antibody (IgG) 1mg/ml in PBS
50% glycerol filter-sterilized

Specificity: Specific to mouse Nestin not tested with other species.



Nestin is an intermediate filament protein that is expressed in stem cells and progenitor cells in the mammalian central nervous system (CNS) during development. Nestin is replaced in the adult organism by other intermediate filament proteins however it may be re-expressed under certain pathological conditions such as ischemia inflammation brain injury and neoplastic transformation. Nestin has been detected in many kinds of tumors especially in tumors derived from the CNS therefore it is considered to be a marker for cancer stem cells in neurogenic tumors.


References:. Iriuchishi H. Neovascular niche for human myeloma cells in immunodeficient mouse bone
PLoS One. 2012;7(2):e30557. PMID: 22347385 IHC-F (mouse)
 
 
Code
Quantity
                  Price
 
73-100
200 ug
245 USD

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