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Code:65-059

Hepatitis C virus (HCV) is a small (55-65 nm in size) enveloped positive sense single-stranded RNA virus in the family Flaviviridae and the principal cause of hepatitis. The polyprotein encoded is processed into four structural proteins (core envelope1 and 2 and p7) and six non-structural proteins (NS2 3 4a 4b 5a and 5b) necessary for viral replication. NS4a protein (54 amino acids) forms a comlex with NS3 and functions as a cofactor for NS3 protease activity.

Applications
1. Western blotting 2. Immunofluorescence staining 3. ELISA 4. FACS

Immunogen: A region of NS4 protein of HCV genotype 1b expressed in E.coli. The epitope of this antibody was mapped to the N-terminal region of the NS4 protein (NS4a).
Congugate: FITC conjugated [FITC] / [IgG] = 10.4

Isotype: Mouse IgG2b kappa

Form: 1.4 mg/ml in PBS 50% glycerol filter-sterilized

Specificity: Specific to human HCV NS4a protein of genotype 1b. Not tested in other genotypes..
 
 
Code
Quantity
                  Price
 
65-059
50 ug
310 USD

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