Registration
          
Cart
      
Infomation of Product
Sort
All topics:1 topics
1 topic~1 topics
Product
 
Information
Code:63-143

Schizosaccharomyces pombe Sds23 protein functions to facilitate the progression in anaphase in mitotic cell cycle. For initiating anaphase in fission yeast PP1 (protein phosphatase 1) and 20S cyclosome/APC are required. Thesds23 gene is a multicopy suppressor for mutations in PP1 and the 20S cyclosome/APC implying that the gene dosage increase can relieve the requirement for PP1 and the cyclosome/APC for the onset of anaphase. The sds23 gene encodes a 408 aa product and appears to be conserved. The sds23 gene is not essential for cell viability but in the sds23 deletion mutant the progression of anaphase and cytokinesis are retarded and cell shape is aberrant. Therefore Sds23 protein is involved in progression in anaphase as well as in cytokinesis and cell shape control. Sds23 is neither physically bound to PP1 nor a subunit of the cyclosome. It possibly regulates the PP1 and 20S cyclosome/APC in an unknown fashion.
 
 
Code
Quantity
                  Price
 
63-143
100 ul
350 USD

About Security  |   Policy  |   Escape  |   Site map  |   Address
Copyright(C) BioAcademia, Inc. 2006. All Rights Reserved.