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Code:63-119

Schizosaccharomyces pombe Dis2 is a serine/threonine protein phosphatase which is highly similar to mammalian type 1 phosphatase (PP1). Protein phosphatases are known to play critical roles in cell cycle regulation in fission yeast. Fission yeast has two type 1 protein phosphatases Dis 2 and Sds21. They are 37 kDa proteins and their amino acid sequences are 80% identical to each other and to mammalian PP1 homologs. Dis 2 and Sds21 are necessary for mitotic chromosome disjunction and have overlapping functions. Their disruptants are lethal only when both genes are disrupted. Dis 2 is known to be enriched in nuclei.
1. Immunoblotting (dilution: 1/300~1/1000)
2. Immunoprecipitation
 
 
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63-119
100 ul
350 USD

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