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62-300

Storage: Ship at 4℃ and store at -20℃

Reactivity: S. cerevisiae Sup35 not tested with other species

Immunogen: Synthetic peptide corresponding to a.a. 494-507 of Sup35

Applications:1) Western blotting (1000~2000 fold dilution)

Product: Rabbit polyclonal antibody purified IgG fraction

Form:   Purified IgG 4 mg/ml in PBS 50% glycerol 0.09% sodium azide

Background: Sup35 protein of S. cerevisiae is the translation termination factor eRF3. The altered conformation of this protein generates the [PSI+] prion phenotype . In this state a dominant cytoplasmically inherited protein aggregates are formed which sequester the normal function of Sup35 thereby nonsense suppressor phenotype is created . The molecular chaperon Hsp104 is necessary for the formation and maintenance of the aggregates .
 
 
 
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62-300
100 ul
421 USD

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