汎用品年度末キャンペーン実施中 〜 2018年3月31日まで
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情報全件数:4件
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製品名
 
製品簡略説明
製品番号: 70-310

Nucleoporin 98 (Nup98) は核膜に埋め込まれた大きな構造体である核膜孔(NPC)の構成成分の一つで
あり、核膜孔の両側に存在する。このタンパク質はGly-Leu-Phe-Gly の繰り返し配列を持っていて、タン
パク質の核移行及びRNA の核外への移行に必須である(1)。Nup98 遺伝子は白血病患者の染色体上で転移
していて種々の遺伝子と融合している(2)。このハイブリドーマは大阪市立大学の立花太郎博士の研究室で
作成された(3)。
用途:
1)ウエスターンブロッテイング 2)免疫染色 3)ELISA 4) ドットブロッテイング
性質: 本抗体を細胞質に注入すると核膜孔に蓄積し、内在性のRan タンパク質の核局在を阻害する。
抗原: 組換え体Nup98 タンパク質 (アミノ酸 1-466)
 
 
商品コード
容量
価格
 
70-310
100 ug
32,000円(税抜)

製品名
 
製品簡略説明
製品番号:70-345

Nucleoporin 98 (Nup98) is a component of nuclear pore complex (NPC) which is a large protein assembly embedded in the nuclear envelope and highly conserved in eukaryotes. It is localized on both nuclear and cytoplasmic side of NPC. This protein contains glycine-leucine-phenylalanine-glycine (GLFG) amino acid repeats and plays a critical role in nuclear trafficking. Nup98 also plays a specific role in the RNA export. In addition Nup98 plays roles in several important biological events such as gene expression mitotic checkpoint and pathogenesis
Nup98 gene is fused to a variety of partner genes in human myeloid and T-cell malignancies via chromosomal translocation.
In ciliates a unicellular organism having two functionally distinct nuclei GLFG-Nup98 is present in one of the nuclei and a distinct Nup98 ortholog is present in the other nucleus and these different Nup98s participate in a nucleus-selective transport mechanism.
 
 
商品コード
容量
価格
 
70-345
100 ug
39,000円(税抜)

製品名
 
製品簡略説明
製品番号:70-346

Nucleoporin 98 (Nup98) is a component of nuclear pore complex (NPC) which is a large protein assembly embedded in the nuclear envelope and highly conserved in eukaryotes. It is localized on both nuclear and cytoplasmic side of NPC. This protein contains glycine-leucine-phenylalanine-glycine (GLFG) amino acid repeats and plays a critical role in nuclear trafficking. Nup98 also plays a specific role in the RNA export. In addition Nup98 plays roles in several important biological events such as gene expression mitotic checkpoint and pathogenesis
Nup98 gene is fused to a variety of partner genes in human myeloid and T-cell malignancies via chromosomal translocation.
In ciliates a unicellular organism having two functionally distinct nuclei GLFG-Nup98 is present in one of the nuclei and a distinct Nup98 ortholog is present in the other nucleus and these different Nup98s participate in a nucleus-selective transport mechanism.
 
 
商品コード
容量
価格
 
70-346
100 ug
39,000円(税抜)

製品名
 
製品簡略説明
製品番号:70-347

Nucleoporin 98 (Nup98) is a component of nuclear pore complex (NPC) which is a large protein assembly embedded in the nuclear envelope and highly conserved in eukaryotes. It is localized on both nuclear and cytoplasmic side of NPC. This protein contains glycine-leucine-phenylalanine-glycine (GLFG) amino acid repeats and plays a critical role in nuclear trafficking. Nup98 also plays a specific role in the RNA export. In addition Nup98 plays roles in several important biological events such as gene expression mitotic checkpoint and pathogenesis
Nup98 gene is fused to a variety of partner genes in human myeloid and T-cell malignancies via chromosomal translocation.
In ciliates a unicellular organism having two functionally distinct nuclei GLFG-Nup98 is present in one of the nuclei and a distinct Nup98 ortholog is present in the other nucleus and these different Nup98s participate in a nucleus-selective transport mechanism.
 
 
商品コード
容量
価格
 
70-347
50 + 50 ug
39,000円(税抜)

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