Validation: Specificity validated with knock-out mice.
Storage: Ship at 4℃ and store at -20℃.
Reactivity: Mouse. Not tested in other species.
1. Western blotting (1/1000 dilution)
2. Immunoprecipitation (1/100)
3. Immunohistochemistry (1/100-1/500)
Immunogen: Two synthetic peptides corresponding to the C-terminal regions of mousePDILT
Form: Whole rabbit antiserum added with 0.1% sodium azide.
Function: PDILT cooperates with the testis-specific calreticulin-like chaperone calsperin(CALR3) in the endoplasmic reticulum and plays an indispensable role in thedisulfide-bond formation and folding of ADAM3. Pdilt(-/-) mice were male infertile becauseADAM3 could not be folded