DDX3X (662aa 73.2 kDa) is a member of DEAD box proteins characterized by the conserved motif
Asp-Glu-Ala-Asp (DEAD) which are putative RNA helicases. They are implicated in a number of cellular
processes involving alteration of RNA secondary structure such as translation initiation nuclear and
mitochondrial splicing and ribosome and spliceosome assembly. Based on their distribution patterns
some members of this family are believed to be involved in embryogenesis spermatogenesis and cellular
growth and division. This gene encodes a DEAD box protein which interacts specifically with hepatitis C
virus core protein resulting a change in intracellular location. This gene has a homolog located in the
nonrecombining region of the Y chromosome. The protein sequence is 91% identical between this gene
and the Y-linked homolog. Alternative splicing results in multiple transcript variants.
1. Western blotting (1/1000~ 1/5000)
2. Immunofluorescence staining (1/500)
Other applications have not been tested.
Reactivity: Reacts with DDX3 of human and rodents. Not tested with
Immunogen: Purified full-lenght human DDX3X fused with GST
Form:::: Undiluted anti rabbit serum added with 0.05 % sodium azide
Storage: Shipped at 4℃. Upon arrival aliquot and store at -20℃.